Id hope by this point you’ve already reseated not only the card but the connection to the card as well ?.
Possibly a faulty card.
I'm guessing by card you mean the optic? These are QSFP28 ports.
Clean fiber as Daniel mentioned, reseat optic, the usual stuff. Try replacement parts you have in stock, then go from there replacing the cheapest components first before trying to replace the more costly ones.
What manufacturer optic are you using, and what sort of media specifically?