Hi all. So I may have fixed this for my end, and hopefully others may be able to use the same fix. After a tip from Karl Auerbach and this link: https://developer.apple.com/forums/thread/97805 ... I was able to fix the problem by disabling Bluetooth. However, disabling Bluetooth was not enough. I also had to disable all Location Services. After that, I re-enabled Location Services and only allowed for two features: - NetSpot - Find My Mac With just those two location services, as well as Bluetooth disabled, I have no more high jitter. App performance like Zoom and Youtube uploads are now crisp, with 0.0% packet loss. So looks like that Bluetooth is a huge problem. Confirmed by opening the "Console" app, and adding "scan" in the filter bar, top right. A peak latency of 13.5ms after 300 packets: Marks-MacBook-Pro.local (172.16.0.239) 2020-10-30T21:06:05+0200 Keys: Help Display mode Restart statistics Order of fields quit Packets Pings Host Loss% Snt Last Avg Best Wrst StDev 1. 172.16.0.254 0.0% 300 3.1 4.8 2.2 13.5 1.9 Mark.