Analysing traces for performance bottlenecks

Hi, Are there any packages (or Wireshark options that I've missed) that can follow a TCP stream and determine the limiting factor on throughput. E.g Latency, packet loss, out of sequence packets, window size, or even just the senders rate onto the wire. I know how to analyse a trace by hand for performance issues, but it's relatively time consuming. Googling for variations on "Analyse TCP stream limit throughput" didn't find anything. Sam